Abstract Summary
Objective: This study examines the potential health benefits of ashwagandha extract, focusing on its effects on stress, anxiety, sleep quality, cognitive function, and overall well-being.
Context: Ashwagandha (Withania somnifera), a cornerstone of Ayurvedic medicine, is traditionally utilized for its adaptogenic properties, aiding in stress management and promoting general health. Recent scientific investigations have explored its efficacy in various health domains.
Methods Used
Approach: A comprehensive review of clinical studies and scientific literature was conducted to evaluate the effects of ashwagandha extract on various health outcomes.
Data Collection: Peer-reviewed articles and clinical trials were sourced from reputable databases, including PubMed, ScienceDirect, and the National Institutes of Health (NIH). Keywords such as "ashwagandha extract benefits," "Withania somnifera clinical studies," and "ashwagandha health effects" guided the search. Studies were selected based on relevance, sample size, and methodological rigor.
Researchers' Summary of Findings
Impact on Health: Clinical evidence suggests that ashwagandha extract may offer several health benefits:
Stress and Anxiety Reduction: Multiple studies indicate that Ashwagandha supplementation can significantly reduce stress and anxiety levels. A systematic review identified that doses ranging from 240 mg to 1,250 mg per day led to decreased stress and anxiety, improved sleep quality, and reduced serum cortisol levels compared to placebo groups.
Improved Sleep Quality: Research has shown that Ashwagandha may enhance sleep quality. In a study involving 50 adults aged 65–80, participants who took 600 mg of ashwagandha root extract daily for 12 weeks experienced significant improvements in sleep quality and mental alertness upon waking compared to the placebo group.
Enhanced Cognitive Function: Some studies suggest that ashwagandha may improve cognitive functions, including memory and attention. A review of five clinical studies found early evidence that ashwagandha could benefit cognitive functioning in specific populations, such as older adults with mild cognitive impairment and people with schizophrenia.
Potential Testosterone Increase and Fertility Improvement in Men: Limited evidence indicates that ashwagandha supplementation may lead to increased testosterone levels and improved fertility in men.
Health Implications: While ashwagandha extract appears to offer various health benefits, it is essential to consider potential adverse effects.
Adverse Reactions: Some individuals may experience side effects such as gastrointestinal discomfort, drowsiness, or allergic reactions.
Conclusion: Ashwagandha extracts potentially reduce stress and anxiety, improve sleep quality, and enhance cognitive function. However, individual responses may vary, and some users may experience adverse effects. It is advisable to consult with healthcare professionals before starting Ashwagandha supplementation to ensure safety and suitability.
DOI: 10.1097/MD.0000000000017174
