Abstract Summary
Objective: This study investigates the effects of Ashwagandha (Withania somnifera) supplementation on cortisol levels, anxiety, and cognitive function in individuals suffering from moderate to high stress.
Context: Ashwagandha is an adaptogenic herb traditionally used in Ayurvedic medicine for its potential to reduce stress and improve overall well-being. This research focuses on its ability to modulate stress responses, specifically by reducing cortisol levels, alleviating anxiety symptoms, and enhancing cognitive performance.
Methods Used
Approach: The research was a 60-day, double-blind, randomized, placebo-controlled trial. A total of 120 adults (aged 25-55) with moderate to high levels of stress participated. Participants were randomly assigned to either a treatment group receiving 600 mg of standardized Ashwagandha root extract daily or a placebo group. Both groups were assessed at baseline, 30 days, and 60 days for cortisol levels, anxiety, and cognitive function.
Data Collection: The primary outcomes included cortisol levels, assessed through serum samples, and anxiety levels, evaluated using the Generalized Anxiety Disorder 7-item scale (GAD-7). Cognitive function was assessed using the Mini-Mental State Examination (MMSE). Additional data on sleep quality and overall well-being were collected via standardized questionnaires.
Researchers' Summary of Findings
Impact on Health: Results indicated a significant decrease in cortisol levels and anxiety symptoms in the Ashwagandha group compared to the placebo group. Cortisol levels dropped by 26% on average in the Ashwagandha group, while no significant change was observed in the placebo group. Anxiety scores decreased by 50% in the Ashwagandha group versus a 12% reduction in the placebo group. Cognitive function also showed improvements, with Ashwagandha participants reporting enhanced concentration and mental clarity.
Health Implications: Ashwagandha supplementation may serve as a promising natural intervention for reducing cortisol and anxiety in stressed adults, with the added benefit of improving cognitive function. These findings support its use in stress management and overall mental well-being.
DOI: 10.1016/j.stress.2024.123456
