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Abstract SummaryObjective: This study evaluates the effect of Ashwagandha supplementation on testosterone levels and fertility markers in men with low sperm count and suboptimal reproductive health. Context: Ashwagandha has been traditionally used in Ayurvedic medicine to enhance male fertility and vitality. The herb is believed to improve sperm quality and testosterone production, making it a candidate for natural fertility enhancement in men with reproductive challenges. Methods UsedApproach: This was a 12-week randomized, double-blind, placebo-controlled trial involving 60 men aged 30-50 with diagnosed low sperm count and suboptimal testosterone levels. The participants were divided into two groups: the treatment group received...

Abstract Summary Objective: This study investigates the effects of Ashwagandha (Withania somnifera) on testosterone levels in healthy adult males. Context: Ashwagandha is an adaptogen widely used in traditional medicine to promote vitality and well-being. Emerging research suggests that it may have a positive influence on male reproductive health, particularly testosterone levels. This study aims to explore the potential of Ashwagandha to boost testosterone and improve reproductive outcomes in healthy men. Methods Used Approach: A randomized, placebo-controlled, double-blind study was conducted over 16 weeks. The trial included 50 men aged 25-40, all of whom had normal testosterone levels at the beginning...

Abstract Summary Objective: This study investigates the gastrointestinal side effects of Ashwagandha (Withania somnifera) supplementation in healthy adults. Context: While Ashwagandha is widely recognized for its benefits in stress reduction and immune support, there is growing evidence of potential gastrointestinal disturbances as a side effect of long-term supplementation. This study evaluates the incidence of gastrointestinal symptoms such as nausea, diarrhea, and abdominal pain associated with Ashwagandha use. Methods Used Approach: A 10-week observational study was conducted on healthy adults aged 30-55 who were self-administering Ashwagandha root extract (600 mg daily). Participants were monitored for the onset of gastrointestinal symptoms and...

Abstract Summary Objective: This study examines the potential side effects of Ashwagandha (Withania somnifera) on thyroid function in individuals with subclinical hypothyroidism and those with normal thyroid function. Context: Ashwagandha is commonly used as an adaptogen to promote overall health and well-being. However, there are concerns that the herb may influence thyroid hormone production, particularly in individuals with pre-existing thyroid conditions. This study investigates the potential adverse effects of Ashwagandha on thyroid function by evaluating changes in thyroid-stimulating hormone (TSH), free T3, and free T4 levels. Methods Used Approach: A randomized, placebo-controlled, double-blind trial was conducted over a 12-week period....