Abstract Summary
Objective: This study investigates the potential health benefits of ashwagandha (Withania somnifera), focusing on its effects on stress reduction, cognitive function, physical performance, hormonal balance, and overall well-being.
Context: Ashwagandha is a prominent herb in Ayurvedic medicine, traditionally used to enhance vitality and manage various health conditions. Its adaptogenic properties are believed to help the body cope with stress, but scientific validation is essential to substantiate these claims.
Methods Used
Approach: The study employs a comprehensive literature review of clinical trials and experimental studies examining ashwagandha's efficacy. Databases such as PubMed and clinical trial registries were searched for relevant studies up to March 2025.
Data Collection: Data were collected from randomized controlled trials (RCTs), observational studies, and meta-analyses focusing on ashwagandha's impact on stress, anxiety, cognitive function, physical performance, hormonal levels, and safety profiles.
Researchers' Summary of Findings
Impact on Health:
Stress and Anxiety Reduction: Several RCTs have demonstrated that ashwagandha supplementation significantly reduces stress and anxiety levels. For instance, a study involving 60 participants reported a 27.9% reduction in cortisol levels after 60 days of supplementation.
Cognitive Function: Emerging evidence suggests that ashwagandha may enhance cognitive abilities, including memory and attention. However, more extensive studies are required to confirm these benefits.
Physical Performance: Ashwagandha has been linked to improvements in strength and endurance. A study with 57 young male subjects showed significant gains in muscle strength and size over an 8-week resistance training program.
Hormonal Effects: Research indicates that ashwagandha can increase testosterone levels and improve reproductive health in men. A study observed a 14.7% increase in testosterone among male participants after 8 weeks of supplementation.
Sleep Quality: Ashwagandha supplementation has been associated with better sleep quality. Participants in a study reported improved sleep parameters after taking the herb for six weeks.
Health Implications: Incorporating ashwagandha into a balanced diet may offer various health benefits, particularly in stress management, physical performance, and hormonal health. However, individuals should consult healthcare providers before starting supplementation, especially if they have underlying health conditions or are on medication.
Sustainability: Sourcing ashwagandha from reputable suppliers who practice sustainable farming ensures the purity of the product and supports environmental conservation efforts.
DOI: 10.1007/s00424-025-00983-2
