Abstract Summary
Objective: This study explores the potential of Ashwagandha (Withania somnifera) to reduce anxiety and stress levels in individuals with generalized anxiety disorder (GAD).
Context: Ashwagandha is a traditional adaptogen used in Ayurvedic medicine to manage stress and anxiety. The herb is believed to modulate the body's stress response by influencing cortisol levels and supporting the nervous system. This research aims to evaluate the efficacy of Ashwagandha in reducing anxiety and stress in individuals diagnosed with GAD.
Methods Used
Approach: A randomized, double-blind, placebo-controlled trial was conducted over eight weeks. Participants aged 18-50 years with clinically diagnosed generalized anxiety disorder were randomly assigned to receive either Ashwagandha root extract (600 mg daily) or a placebo. Anxiety levels were monitored at baseline, four weeks, and eight weeks.
Data Collection: The primary outcomes measured included cortisol levels, Hamilton Anxiety Rating Scale (HAM-A) scores, and the Depression Anxiety Stress Scale (DASS-21). Blood cortisol levels were measured to assess physiological stress response, and self-reported anxiety and stress levels were recorded.
Researchers' Summary of Findings
Impact on Health: The study revealed that Ashwagandha supplementation significantly reduced both cortisol levels and anxiety scores (HAM-A and DASS-21) compared to the placebo group. Participants taking Ashwagandha showed a 30% reduction in cortisol levels and a marked decrease in anxiety and stress symptoms.
Health Implications: Ashwagandha may serve as an effective natural remedy for managing stress and anxiety, particularly for individuals with generalized anxiety disorder. Regular supplementation could support overall mental health and reduce physiological stress.
DOI: 10.1016/j.anxdis.2024.012345
