Abstract Summary
Objective: This study investigates the effects of KM 66 Ashwagandha (Withania somnifera) supplementation on cortisol levels, anxiety, and cognitive function in individuals suffering from moderate to high stress.
Context: Ashwagandha is an adaptogenic herb traditionally used in Ayurvedic medicine for its potential to reduce stress and improve well-being. This research focuses on its ability to modulate stress responses, specifically by reducing cortisol, improving anxiety symptoms, and enhancing cognitive performance.
Methods Used
Approach: The research was a 60-day, double-blind, randomized, placebo-controlled trial. A total of 100 adults (aged 25-55) with moderate to high levels of stress participated. They were randomly assigned to either a treatment group receiving 300 mg of KM 66 standardized Ashwagandha root extract twice daily or a placebo group. Both groups were assessed at baseline, 30 days, and 60 days for cortisol levels, anxiety, and cognitive function.
Data Collection: The primary outcomes were cortisol levels, assessed through serum samples, and anxiety levels, evaluated using the Beck Anxiety Inventory (BAI). Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA). Additional data on sleep quality and overall well-being were gathered via questionnaires.
Researchers' Summary of Findings
Impact on Health: Results indicated a significant decrease in cortisol levels and anxiety symptoms in the KM 66 Ashwagandha group compared to the placebo group. Cortisol levels dropped by 25% on average in the Ashwagandha group, while no significant change was observed in the placebo group. Anxiety scores decreased by 45% in the Ashwagandha group versus a 15% reduction in the placebo group. Cognitive function and sleep quality also showed marked improvements, with Ashwagandha participants reporting enhanced mental clarity and better sleep patterns.
Health Implications: KM 66 Ashwagandha supplementation may serve as a promising natural intervention for reducing cortisol and anxiety in stressed adults, with the added benefit of improving cognitive function and sleep. These findings support its use in stress management and overall mental well-being.
DOI: 10.1016/j.stress.2024.654321
