Abstract Summary
Objective: To evaluate the efficacy of curcumin, the active component of turmeric, in alleviating joint pain and improving physical function in individuals with osteoarthritis.
Context: Osteoarthritis is a prevalent degenerative joint disease characterized by pain and reduced mobility. Curcumin is renowned for its anti-inflammatory and antioxidant properties, making it a potential therapeutic agent for joint pain relief.
Methods Used
Approach: A randomized, double-blind, placebo-controlled trial was conducted over 12 weeks. Participants diagnosed with knee osteoarthritis were assigned to receive either 1,000 mg of curcumin daily or a placebo.
Data Collection: Primary outcomes were measured using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) for pain and physical function. Secondary assessments included the Visual Analog Scale (VAS) for pain and the 6-minute walk test to evaluate mobility.
Researchers' Summary of Findings
Participants receiving curcumin significantly reduced WOMAC pain scores compared to the placebo group, indicating decreased joint pain. Improvements in physical function and mobility were also observed, as evidenced by enhanced performance in the 6-minute walk test. The curcumin group reported minimal adverse effects, suggesting that curcumin is a safe and effective option for managing osteoarthritis-related joint pain.
DOI: 10.1016/j.joca.2019.01.005
