Learn — Melatonin Safety Guide

Abstract Summary Objective To summarize clinical findings on individuals who should avoid or use caution when taking melatonin, based on physiological, pharmacological, and safety considerations. Context Melatonin is a hormone that regulates the sleep–wake cycle. Although generally safe for short-term use, evidence suggests potential risks for specific groups, including children, pregnant individuals, and those with chronic illnesses or medication sensitivities. Methods Used Approach A focused literature review was conducted using data from PubMed, NIH, Mayo Clinic, and NHS health databases. Emphasis was placed on safety data, pharmacological interactions, and hormonal outcomes. Data Collection Clinical and observational studies were reviewed for...