Abstract Summary
Objective
To assess whether ashwagandha (Withania somnifera) is effective in reducing anxiety symptoms, particularly those related to chronic stress, and to review its safety profile.
Context
Ashwagandha is an adaptogenic herb used in Ayurvedic medicine to support stress resilience and emotional balance. Contemporary research primarily examines its effects in adults with high stress or mild-to-moderate anxiety symptoms, rather than severe anxiety disorders, positioning it as a supportive—not replacement—intervention.
Methods Used
Approach
A concise review of randomized controlled trials and recent systematic reviews was conducted, focusing on human studies that evaluated anxiety outcomes using validated psychological scales and standardized ashwagandha extracts.
Data Collection
Outcomes included changes in anxiety scores, perceived stress, and cortisol levels, along with reported adverse effects and population-specific safety considerations drawn from peer-reviewed literature.
Researchers’ Summary of Findings
Impact on Health
Clinical studies consistently show that ashwagandha supplementation can reduce anxiety and stress scores compared with placebo, often alongside significant reductions in cortisol, suggesting improved regulation of the stress response.
Health Implications
Ashwagandha appears to be a well-tolerated option for stress-related anxiety when used short-term, though evidence is limited by small sample sizes and study heterogeneity. Caution is advised for use during pregnancy, breastfeeding, or in individuals with thyroid disorders, autoimmune conditions, or liver disease.
Sustainability
As a drought-tolerant plant, ashwagandha can be sustainably cultivated, but responsible sourcing and quality control are essential to ensure environmental and consumer safety.
DOI
10.1177/02698811231200023
