Abstract Summary
Objective: This research examines the potential health benefits of Boswellia serrata extract, focusing on its effects on reducing chronic pain and inflammation in individuals with osteoarthritis and other inflammatory conditions.
Context: Boswellia serrata, commonly known as Indian Frankincense, has been utilized in traditional medicine for its anti-inflammatory properties. Recent scientific studies have explored its efficacy in alleviating chronic pain and inflammation, suggesting that Boswellia extract may offer a natural therapeutic option for managing these conditions.
Methods Used
Approach: A comprehensive literature review was conducted, analyzing randomized, double-blind, placebo-controlled trials that assessed the effects of Boswellia serrata extract on chronic pain and inflammation. Studies included varied dosages and durations, focusing on adult populations diagnosed with osteoarthritis and other inflammatory conditions.
Data Collection: Data were extracted on outcome measures such as pain severity (measured by Visual Analog Scale), physical function assessments (using WOMAC scores), and patient-reported quality of life. Both physiological and subjective parameters were considered to provide a holistic understanding of Boswellia's impact.
Researchers' Summary of Findings
Impact on Health: The analysis revealed that Boswellia serrata supplementation is associated with significant reductions in chronic pain and improvements in physical function. Several studies reported decreased pain scores and enhanced mobility in participants receiving Boswellia extract compared to placebo groups. These effects are attributed to Boswellia's anti-inflammatory properties, particularly the inhibition of pro-inflammatory enzymes such as 5-lipoxygenase, leading to reduced production of inflammatory mediators.
Health Implications: Boswellia serrata extract appears to be a promising natural supplement for managing chronic pain and inflammation in individuals with osteoarthritis and other inflammatory conditions. Its potential benefits in reducing inflammation and enhancing quality of life make it a valuable addition to treatment regimens. However, individuals should consult healthcare providers before starting Boswellia supplementation, especially if they have underlying health conditions or are taking other medications.
DOI: 10.1186/ar2461