Abstract Summary
Objective
This report explores how turkey tail mushrooms (Trametes versicolor) may support immune health and act as a helpful companion in cancer care. We take a closer look at the compounds believed to be behind these benefits—mainly PSK (polysaccharide-K) and PSP (polysaccharide-peptide)—and consider what current research says about their practical use.
Context
Turkey tail mushrooms have a rich history in traditional medicine, particularly in countries such as China and Japan. They're often brewed into teas or extracts thought to boost health. More recently, scientists have identified key compounds in turkey tail that appear to help the immune system do its job more effectively. These findings have sparked interest in how the mushroom may help people, especially those undergoing cancer treatments.
Methods Used
Approach
We compiled research from reliable sources, including peer-reviewed journals available in PubMed and Google Scholar. The focus was on how turkey tail’s active compounds affect the immune system and how they’re being studied as part of supportive cancer care.
Data Collection
The review included a range of studies—some conducted in the laboratory (in vitro), others on animals or humans (in vivo and clinical trials). We prioritized studies that looked specifically at the effects of PSK and PSP on immune activity and cancer outcomes, including research related to breast, stomach, and colon cancers.
Researchers’ Summary of Findings
Health Implications
Turkey tail mushrooms contain natural substances that may encourage your immune system to work more efficiently. These include compounds that help the body produce immune-signaling proteins (cytokines) and activate cells that fight off harmful invaders, like viruses and tumor cells. Some clinical research suggests that when used in conjunction with conventional cancer treatments, turkey tail may enhance treatment outcomes and help the body recover more effectively.
It’s also worth noting that turkey tail acts as a prebiotic—essentially food for the good bacteria in your gut. Since gut health and immune health are closely connected, this could be another reason why people experience overall benefits when adding turkey tail to their routine.
Sustainability
Turkey tail mushrooms naturally grow on decaying logs and play a role in keeping forest ecosystems healthy. The good news is they don’t need to be foraged from the wild to be useful. They can be grown sustainably using leftover agricultural materials, such as sawdust, making them an eco-friendly option for health supplements.
DOI
10.1186/s12906-019-2681-7
