Learn — Melatonin Dosage

Abstract Summary Objective The objective of this research is to determine the most effective and safest dosage of melatonin for improving sleep outcomes, with a focus on sleep latency, duration, and quality in both general and clinical populations. Context Melatonin, a hormone secreted by the pineal gland, regulates circadian rhythms and sleep-wake cycles. It is widely used as a supplement for conditions like insomnia, jet lag, and circadian rhythm disorders. While it is available over-the-counter, dosage recommendations vary widely. Clinical data suggests that lower doses may mimic physiological levels more effectively, while higher doses can cause side effects or lose...