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Abstract Summary Objective: This study investigates the role of Ashwagandha (Withania somnifera) in enhancing immune function, with a focus on its immunomodulatory properties, adaptogenic effects, and synergistic potential with other natural compounds. Context: Ashwagandha, a cornerstone of Ayurvedic medicine, is renowned for its ability to reduce stress and promote balance within the body. This research delves into its specific impact on the immune system, exploring mechanisms such as cytokine modulation, anti-inflammatory activity, and its effects on natural killer (NK) cells. The study also reviews its application in dietary practices and supplementation to support holistic wellness. Methods Used Approach: A multidisciplinary review synthesizing findings...

Abstract Summary Objective: This study explores the culinary applications of Ashwagandha (Withania somnifera) in recipes designed to enhance health and well-being, focusing on its adaptogenic properties, taste integration, and potential health benefits. Context: Ashwagandha, an adaptogenic herb central to Ayurvedic medicine, is increasingly used in cooking for its potential health benefits, including stress reduction, improved cognitive function, and enhanced immunity. This study investigates recipes incorporating Ashwagandha to assess its adaptability in various cuisines and its impact on flavor, nutrition, and user satisfaction. Methods Used Approach: A mixed-method study combining recipe trials with sensory evaluations and nutritional analyses. The research involved...

Abstract Summary Objective: To evaluate the effects of Ashwagandha (Withania somnifera) supplementation on physical performance, including muscle strength, cardiorespiratory fitness, and fatigue/recovery, in healthy individuals. Context: Ashwagandha is traditionally recognized for its adaptogenic properties, potentially enhancing physical performance and vitality. This study systematically reviews and analyzes clinical trials to assess its efficacy in improving physical performance metrics. Methods Used Approach: A systematic review and Bayesian meta-analysis were conducted, adhering to PRISMA guidelines, to evaluate the impact of Ashwagandha supplementation on physical performance. Data Collection: Databases including PubMed, ScienceDirect, and Google Scholar were searched for clinical trials up to 2020. Thirteen...

Abstract Summary Objective: To evaluate the impact of ashwagandha (Withania somnifera) supplementation on cortisol levels in individuals experiencing stress. Context: Ashwagandha, a traditional adaptogenic herb, is reputed for its stress-reducing properties. This study investigates its efficacy in modulating cortisol, a primary stress hormone. Methods Used Approach: A systematic review and meta-analysis of randomized controlled trials (RCTs) assessing the effects of ashwagandha on cortisol levels. Data Collection: Comprehensive searches were conducted across databases including PubMed, EMBASE, and Scopus up to December 2023. Inclusion criteria encompassed RCTs involving ashwagandha supplementation with reported cortisol measurements. Researchers' Summary of Findings The analysis incorporated nine...