Learn — Ashwagandha contraindications

Safety Profile of Ashwagandha: Contraindications, Interactions, and Risk Groups

Abstract Summary Objective To identify populations who should not take ashwagandha (Withania somnifera) by evaluating clinical safety data, regulatory guidance, and documented adverse effects, with emphasis on contraindications, high-risk health conditions, and drug interactions. Context Ashwagandha is widely promoted for stress reduction, sleep support, and hormonal balance. As its use has expanded globally, safety concerns have emerged regarding its suitability for certain individuals. Regulatory agencies and clinical researchers have highlighted specific groups for whom ashwagandha may pose health risks, particularly related to pregnancy, liver health, autoimmune activity, and medication interactions. Methods Used Approach A narrative review of safety-focused literature was...

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