Learn — Ashwagandha safety

Abstract Summary Objective To examine the effects of daily ashwagandha supplementation on stress levels, cortisol regulation, sleep quality, cognitive clarity, and overall safety. Context Ashwagandha (Withania somnifera) is an adaptogenic herb used in Ayurvedic medicine to support stress regulation. Its active compounds, withanolides, influence the hypothalamic-pituitary-adrenal axis and neurotransmitter balance, contributing to reduced stress, improved mood, and better sleep. Effects vary depending on extract quality, dosage, and individual response. Methods Used Approach This summary is based on systematic reviews and randomized controlled trials evaluating daily ashwagandha use over periods of six to twelve weeks. Data Collection Outcomes assessed included perceived...